We provide R&D services and look for partnerships with pharmaceutical companies to satisfy the demand for novel drug delivery systems, and innovative and efficient treatments.
CHANGING THE WAY DRUGS ARE DELIVERED
Efficient and effective drug delivery systems are vital in drug development. With our cutting-edge microencapsulation technology, we introduce timed and targeted drug delivery. Our programmed-shell microcapsules deliver drugs at the right place, in the right dosage, and at the right time, bringing treatment outcomes to the next level.
CREATE SMART DRUGS WITH OUR CONTROLLED-RELEASE MICROCAPSULES
The success of drug therapies is largely impacted by adequate and efficient drug delivery systems. In addition to overcoming the existing challenges of conventional drug therapy, our advanced microencapsulation technology enhances therapeutic drug efficacy. We introduce controlled and targeted drug delivery, offering great potential for the pharmaceutical industry.
Possessing unique microencapsulation capabilities, we can precisely programme the time of drug release, achieving efficacy at an entirely different level. While slow-release drugs are not new to the market, we move one step forward by introducing a timed-release function, a new way to deliver drugs. Our programmed-shell microcapsules can be programmed to open and release drugs at the desired time and with the required kinetics. The microcapsules can also be magnetically targeted to a specific site of the body.
We also introduce the release-on-demand mechanism. We ensure the drug release triggered by changes in the environment, such as pH, ionic strength (salinity), solvent polarity, and temperature, or triggered by external stimuli, for example, ultrasound and light (near-infrared laser) or triggered by the cancer-specific environment. We developed microcapsules that release drugs in cancer cells, but not in stem cells.
We deliver drugs into the body at the right place, in the right dosage, and at the right time. Controlled and targeted drug release is a reliable means to deliver drugs to the target site to obtain optimum benefits and maintain the desired concentration without side effects. The timed and targeted release functions result in improved drug efficacy, prolonged action, and optimal dosage. Our technology is a tool to reduce off-target effects that can lead to side effects ranging in severity from mild to life-threatening. Drugs can also be delivered in smaller dosages due to less drug waste on incorrect targets.
Our smart microcapsules release drugs according to pre-defined scenarios:
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RELEASE WITH THE REQUIRED KINETICS
Our microcapsules offer precise dosing and controlled release properties.
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TIMED RELEASE
We programme the microcapsule shells to release active substances at the desired time.
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TRIGGERED RELEASE
The microcapsule opening can be triggered by environmental changes (pH, salinity, solvent polarity), external stimuli (ultrasound, NIR laser) or the cancer-specific environment.
Today, different methods have been applied for drug delivery. However, the widespread emulsion spray-drying and microemulsification techniques produce emulsion microdroplets with no shells, meaning they are not microcapsules. The lack of shells makes the controlled and timed release impossible. The emulsification process also limits the selection of active substances. While liposomes and microfluidic solutions are more advanced options, liposomes are highly unstable and expensive, and microfluidics is a costly technique and low yield, making it limited mainly to research purposes.
NO LIMITATION FOR ACTIVE SUBSTANCES
We can encapsulate almost any molecule, from small (down to microelements) to large (DNA, RNA, proteins), making our technology suitable for various applications, including CAR T-cell therapy, vaccines and gene therapy.
FDA-APPROVED BIOCOMPATIBLE AND BIODEGRADABLE POLYMERS
We can choose from a wide range of FDA-approved biocompatible and biodegradable polymers, synthetic or natural. Our microcapsules can satisfy the specific needs of vegetarians and vegans.
HIGH STABILITY
Unlike liposomes and emulsion droplets, our microcapsules are highly stable, making our technology suitable for a wide range of applications.
HIGH LOADING CAPACITY
Our microcapsules can hold high volumes of active substances (cargo-shell ratio up to 10:1).
TARGETED DRUG DELIVERY
PH-TRIGGERED DRUG RELEASE AND TIMED-RELEASE
Mask taste and odour
Mask the taste of bitter drugs or unpleasant odour to improve palatability.
Protect active ingredients
Protect drugs from environmental conditions (moisture, oxidation, stomach pH, heat, sunlight, etc.) and interactions.
Improve bioavailability
Enhance absorption and improve the bioavailability of drugs to increase efficacy and allow optimal dosage delivery.
Increase stability
Increase the stability of drugs resulting in the shelf-life extension.
Reduce hygroscopicity and retard evaporation
Reduce drug hygroscopicity by preventing moisture, which decomposes drugs and reduces their efficacy, as well as retard the evaporation of volatile drugs.
Allow timed and targeted release
Controlled release of drugs at the right time and at the right place to improve efficacy, prolong action, and ensure optimal dosage.
Reduce dosing and gastric irritation
Reduce drug dosing and eliminate gastrointestinal irritation caused by gastric irritant drugs, thus ultimately improving patient compliance.
Allow easy handling and storage
To modify drugs’ physical characteristics for easy handling and storage. A liquid can be transformed into powder-looking capsules.
PARTNER WITH US
We are looking for partnerships with pharmaceutical companies to co-develop and co-promote our innovative drug delivery systems to bring treatment effectiveness to the next level.