We provide R&D services and look for partnerships with manufacturers of dietary supplements to meet the changing, diversifying expectations of consumers embracing health in many aspects of their lives.
MEET INCREASING CONSUMER DEMAND FOR PRODUCTS WITH PROVEN HEALTH BENEFITS
Consumer habits are changing. Today, the trend is towards a healthier lifestyle leading to a growing demand for dietary supplements to prevent diseases, improve cognition and digestion, and enhance physical performance, energy and longevity. With our unique microencapsulation technology and innovative delivery systems, we will help you satisfy consumers’ demand for supplements with high bioavailability and the highest possible efficacy. We will help differentiate your product offerings, innovate and experiment.
WE INTRODUCE CONTROLLED-RELEASE MICROCAPSULES
SMART MICROCAPSULES WITH CONTROLLED AND TIMED-RELEASE FUNCTIONS
Today, despite the introduction of powders and effervescent powders, liquids, gummies, chewable tablets, and lozenges, traditional formats of dietary supplements, such as tablets, hard capsules and softgel capsules, still dominate the mainstream dietary supplements industry. At the same time, different methods have been applied to improve delivery systems of dietary supplements for increased efficacy, such as sustained-release formulations. However, while the slow release over an extended period of time became possible, the market still does not offer the release at a defined point in time. In addition, over the last 2 decades, liposomal formulations have become the most readily available delivery methods. However, liposomal delivery suffers from two major drawbacks – instability and lack of controlled-release function. We are moving one step forward.
Our CSO pioneered programmed-shell microcapsules with a controlled release, a new way to deliver active substances. Introducing controlled and timed-release functions will enable the manufacturers to greatly improve the efficacy of dietary supplements and reduce the number of required daily intakes. Our advanced microencapsulation technology provides a versatile tool for the controlled and targeted delivery of active substances. And all this at a low price. Production costs are mainly determined by the price of polymers and encapsulated active substances, representing a fraction of the final price.
WE OFFER A BETTER ALTERNATIVE TO LIPOSOMES
Liposomes became a widespread delivery system for active substances. However, they are known for poor chemical and physical stability, requiring specific conditions in order to remain stable, including pH, leakage and fusion of encapsulated compounds, limited control over release function, low loading capacity and high cost for large-scale production. Another popular encapsulation system is the emulsification of cargo into microdroplets. Similarly to liposomes, emulsion droplets are unstable and lack controlled release function, enabling only passive elution.
In contrast, our microcapsules are highly stable. Our technology creates a physical barrier isolating and protecting active ingredients against degrading factors, such as heat, sunlight, moisture, oxidation, or incompatibility and interactions with other ingredients. It also masks off-flavour notes and unappealing taste or colour, making redundant expensive flavourings, sweeteners, colourings, and other masking agents. Effectively sealing the content, the microcapsules are stable, invisible, tasteless and odourless. Our programmed-shell microcapsules are biocompatible and biodegradable, able to hold massive payloads, versatile, applicable for the incorporation of any active substances, and suitable for large-scale, cost-effective production.
Highly stable.
The shell isolates and protects active ingredients against degrading factors, incompatibility and interactions with other ingredients.
Possess the functions of controlled and targeted delivery of active substances.
Versatile, applicable for the incorporation of any active substances, both hydrophilic and hydrophobic.
Able to hold massive payloads.
Suitable for large-scale, cost-effective production.
SMART CONTROLLED-RELEASE MICROCAPSULES FOR DIETARY SUPPLEMENTS
But the most important advantage of our advanced microencapsulation technology and what makes us unique on the market is controlled and timed-release functions. We want to change the entire technology game. With our innovative delivery systems, we want to give consumers a new experience along with all the latest technology. We offer highly stable programmed-shell microcapsules, and we can deliver active compounds into the body at the right place, in the right dosage and at the right time. We can precisely programme the release time of active substances, achieving efficacy at an entirely different level.
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PROLONGED RELEASE
Our microcapsules provide sustained and prolonged release of active substances over periods of hours to months.
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RELEASE WITH THE REQUIRED KINETICS
Our microcapsules provide the release of active substances at a desired rate and dosage.
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TIMED RELEASE
We can programme the microcapsule shells to open and release active substances at a desired time.
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TRIGGERED RELEASE
We introduce the release-on-demand mechanism. The microcapsule opening can be triggered by environmental changes (pH, salinity, solvent polarity, temperature), mechanical action (friction and other forces), external stimuli (ultrasound, NIR laser) or a cancer-specific environment.
HIGHLY STABLE MICROCAPSULES WITH CONTROLLED AND TIMED-RELEASE FUNCTIONS, A NEW WAY TO DELIVER SUPPLEMENTS
We offer high bioavailability and the highest possible efficacy.
WIDE CHOICE OF ACTIVE SUBSTANCES
We can encapsulate any compound, including small molecules and microelements, and even microorganisms. Our microcapsules can hold multiple active substances, making them multifunctional.
WIDE CHOICE OF SHELL MATERIAL
We can choose from a wide range of FDA-approved biocompatible and biodegradable non-toxic polymers, synthetic or natural. We can make shells mono- or multi-layered. Our microcapsules can satisfy the specific needs of vegetarians and vegans.
HIGH STABILITY
Unlike liposomes and emulsion droplets, our polyelectrolyte microcapsules are highly stable.
HIGH LOADING CAPACITY
Our microcapsules can hold high volumes of active substances (active substances: 75-80%, polymers: 20-25%).
WE CAN SOLVE MANY CHALLENGES AND HELP YOU INNOVATE
Our advanced microencapsulation technology provides solutions to overcome many challenges associated with dietary supplements. It will help you develop reliable products with proven health benefits based on scientific evidence and offer advanced personalised solutions with customisable release profiles.
HIGH STABILITY
Unlike liposomes and emulsions, our microcapsules are highly stable, creating a real barrier between active substances and the environment. Many active substances are sensitive to degradation when exposed to the acidic environment of the GIT. Our microcapsules show remarkable stability in the acidic pH, increasing bioavailability and overall efficacy.
TIMED RELEASE
Possessing unique microencapsulation capabilities, we can precisely programme the release time of active compounds, achieving efficacy at an entirely different level. While slow-release formats are not new on the market, we move one step forward by introducing a timed-release function, a new way to deliver dietary supplements. Our smart microcapsules can be programmed to open and release active compounds at a desired time and with the required kinetics.
TARGETED DELIVERY
We introduce an efficient delivery system for transporting active substances to the desired location. Our programmed-shell microcapsules containing active substances remain intact until they reach the target location.
TRIGGERED RELEASE
Our polyelectrolyte multi-layered composite microcapsules provide a versatile tool to create smart delivery systems sensitive to chemical, physical, or mechanical factors. Using our advanced microencapsulation, we achieve a broad range of controlled-release scenarios. Our technology enables the release of active compounds triggered by physiological stimuli, such as pH, ionic strength, and temperature, release triggered by mechanical action (friction and other forces) and remote stimuli, such as ultrasound and near-infrared (NIR) laser light.
CHANGES IN THE ENVIRONMENT
Release of active substances can be triggered by changes in pH, ionic strength (salinity), solvent polarity, and temperature.
EXTERNAL STIMULI
Release of active substances can be triggered by external stimuli, such as ultrasound or near-infrared (NIR) laser light.
MECHANICAL ACTION
Release of active substances can be triggered by mechanical action, such as friction and other forces.
Mask taste, odour and colour
Mask unpleasant taste, odour and colour to improve palatability and product attractiveness.
Protect active ingredients
Protect active compounds from environmental conditions (humidity, oxidation, stomach pH, heat, light, etc.) and interactions with other ingredients.
Improve bioavailability
Improve the bioavailability and enhance absorption to increase efficacy and optimise dosage.
Increase stability
Increase the stability of active compounds resulting in the shelf-life extension.
Improve solubility and dispersibility
Increase solubility of the ingredients, especially of powdered forms, resulting in improved bioavailability.
Controlled and timed release
Controlled release of active substances at the right time and at the right place to improve efficacy, prolong action, and optimise dosage.
Introduce new ingredients
Make it possible to introduce new ingredients to broaden the applications and product range.
Make cost savings
Make redundant artificial flavourings, sweeteners, colourings, and other masking agents and overdosing used to compensate for nutritional losses.
PARTNER WITH US
We seek partnerships with manufacturers of dietary supplements to bring our innovations to the market. Let us know what challenges you are facing and what you would like to improve. We will find a solution for you and will help you design advanced, tailor-made and fully customisable microencapsulation solutions.