MICROCONTAINER FILM TECHNOLOGY FOR PRODUCING NOVEL MATERIALS

We are pioneering novel materials to the market. We developed cutting-edge technology producing novel advanced materials for a variety of industries ranging from biomedical devices to electronics. We will help you bring your business to the next level

 

Our technology offers a cost-effective production of novel advanced materials. Like Dr Leo Baekeland, who invented Bakelite, the world’s first plastic, we developed patterned microcontainer film. This is a polymer film with microcontainers, which are similar to air bubbles in a bubble wrap, only at the micro-level.

 

For electronics:

 

Due to air saturation, our patterned microcontainer air-film reduces the dielectric constant to close to 1, nearly the same as the air, making it a NEW super-structural material. Our material is a breakthrough solution for high-frequency/high-density interconnect printed circuit boards (PCBs) for high-frequency telecommunication (5G), data centres, high-performance computing, etc.

 

For biomedical applications:

 

Instead of air, the microcontainers can contain a drug or another active substance. Made from biocompatible and biodegradable polymers, our patterned microcontainer films are highly-advanced drug-eluting coating materials for catheters, stents, implants, and transdermal patches. They are the world’s first coating material with controlled and prolonged drug release function for optimal dosage and delivery mechanism, significantly improving treatment effectiveness. Our technology also enables the controlled and timed release of encapsulated drugs triggered by ultrasound, pH, temperature, etc.

Microcontainer films technology

The microcontainer films can be designed according to your needs. Our breakthrough technology enables us to produce microcontainers from a wide range of polymers and fill them with almost any substance. The selection of materials will depend on the final application. The production costs are mainly determined by the price of raw materials (polymers, encapsulated active substances).

 

Wide range of polymers

Microcontainer film can be made from a wide range of polymers, including biocompatible and biodegradable polymers for biomedical applications.

 

Controlled and timed release

For biomedical applications, we can programme our microcontainer films to achieve the timed and controlled release of encapsulated substances to increase treatment effectiveness and reduce side effects – prolonged release, timed release (opening of microcontainers at a specific time) and release triggered by ultrasound, light, pH, temperature, etc.

 

Broad choice of active substances

The microcontainers can be filled with air and almost any drug or active substance regardless of molecular weight and solubility.

 

Can be rigid or flexible

By varying the production technology, microcontainer films can be made as rigid as steel or flexible (for wearable electronics).

 

Can sustain high temperatures, pressure and mechanical loads

For electronics, our microcontainers can sustain temperatures of +220 – +370°С and pressures required for PCB manufacturing and they inherit the mechanical strength of polyimides.

 

Flexible shape, size and thickness

The microcontainers’ shape, size and thickness are adjustable to meet the required properties.

Innovative technologies
Electronics
Our microcontainer air-films are an excellent solution for high-frequency/high-density interconnect printed PCBs for 5G telecom, data centres, high-performance computing, etc. due to their ability to reduce energy and signal losses, increase data transmission rate and reduce heat dissipation (overheating).
Innovative technologies
Product tracking systems
Patterned microcontainer films can be used as next-generation invisible magnetic tags, an alternative to the existing RFID tags and QR codes. They can be incorporated into banknotes, paper, plastic, powdered products or liquids and are impossible to counterfeit.
Innovative technologies
Medical devices
Biocompatible and biodegradable microcontainer films can be used to coat catheters, stents, and implants to achieve the controlled and timed release of anti-inflammatory and other drugs, including their release triggered by ultrasound, pH, temperature, etc.
Innovative technologies
Cosmetics
Biocompatible and biodegradable microcontainer films can be used for cosmetic face masks to improve the delivery of hyaluronic acid, antioxidants, ceramides and other skincare products to the skin. The microcontainer films will ensure the slower and gentler release of active compounds improving the skin-repairing effects.
OUR MICROCONTAINER FILM TECHNOLOGY

We coat polydimethylsiloxane (PDMS) stamps with printed microcontainers of the required shape (round, conical, square, etc.) and volume with polyelectrolyte multilayer (PEM) film. The PEM film can be made from a variety of polymers, including biocompatible and biodegradable polymers.

 

Next, the active substance is loaded into the PEM film-coated microcontainers; then, the microcontainers are sealed with another layer of PEM film.

 

Finally, the stamp is removed, and patterned microcontainer film is released.

Device used by our microcontainer films technology

Rolling device to produce patterned microcontainer films and microcontainers

Microcontainer films technology

In addition to microcontainer films, we can produce their derivatives – custom-shaped microcontainers by releasing the microcontainers from the PEM film. In other words, with the same technology, we can produce two types of products:

 

1.    patterned microcontainer films

2.    custom-shaped microcontainers

 

Microcontainers can be of various shapes, forms and sizes.

Microcontainer films technology

References:

 

“Micro-sized “pelmeni” – A universal microencapsulation approach overview” 2021, Materials & Design

“Polyelectrolyte–Graphene Oxide Multilayer Composites for Array of Microchambers which are Mechanically Robust and Responsive to NIR Light” 2018, Macromolecular Rapid Communications

“Patterned Microstructure Fabrication: Polyelectrolyte Complexes vs Polyelectrolyte Multilayers” 2016, Scientific Reports

“Microcontact printing of polyelectrolyte multilayer thin films: Glass–viscous flow transition based effects and hydration methods” 2015, Colloids and Surfaces A

“Micropackaging via layer-by-layer assembly: microcapsules and microchamber arrays” 2014, International Materials Reviews

“Adhesion of Polyelectrolyte Multilayers: Sealing and Transfer of Microchamber Arrays” 2012, Langmuir

“Fabrication and mechanical properties of microchambers made of polyelectrolyte multilayers” 2011, Soft Matter

 

 

Patents and patent applications:

 

“Array of microcapsules for controlled loading of macromolecules, nanoparticles and other nanoscale items and a method of fabricating it” 2013, US8343773B2

“Core-shell composite material” 2018, US20180344650A1

“Biodegradable multilayer nanocapsules for the delivery of biologically active agents in target cells” 2020, US20200375914A1

“Photosensitive capsules and cosmetic and pharmaceutical use thereof” 2021, US10945963B2

 

In total, our team has over 400 scientific publications on patterned microcontainer films and microencapsulation technologies.